Ireland captain Caelan Doris has been passed fit to start Saturday’s Six Nations game against France, but Mack Hansen is ruled out through injury.
Back row Doris missed the win over Wales because of a knee problem, but returns to lead the team as he wins his 50th cap.
Wing Hansen is out with a quad injury, having missed the win over Scotland in round two because of a hamstring issue.
Hansen’s injury means Jamie Osborne switches to the right wing after starting at full-back against Wales.
Osborne, 23, has played on the wing for Leinster, but this will be his first time in the position at Test level.
Ronan Kelleher (neck) remains sidelined, so Rob Herring is set to make his first appearance of the tournament as replacement hooker with Dan Sheehan starting.
Garry Ringrose’s suspension means Bundee Aki returns to partner Robbie Henshaw in midfield, the latter switching to outside centre.
Finlay Bealham returns at tight-head prop and Thomas Clarkson drops to the bench. Tadhg Furlong is still ruled out despite stepping up his rehabilitation from calf and hamstring injuries.
Like Doris, Bealham and Jack Conan are set to win their 50th caps. Conan is one of six forwards named on the bench as Ireland opt to go for a 6-2 split for the first time this year.
After announcing they will retire from Test rugby at the end of the tournament, Peter O’Mahony, Cian Healy and Conor Murray will play in their final home match.
Munster flanker O’Mahony retains his place after starting against Scotland and Wales, while Healy and Murray are named on the bench.
